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In the course of writing about the idea of science in his Systematic Theology, Reformed writer Michael Horton notes that “Britain’s Royal Society was founded by Puritans” (The Christian Faith, 339 n.48).
The Puritans saw no clash, either ontological or methodological, in pursuing science as a response to God’s revelation. The fact that God created the world and created man in His image meant that to find out what God had done was both legitimate, as to fueling an expectation of discovery, and meaningful, because creation had been endowed with its own integrity apart from God while being supervened by God. In this they were in line with the Reformers like Calvin, who said:
Meanwhile being placed in this most beautiful theater, let us not decline to take a pious delight in the clear and manifest works of God. For as we have elsewhere observed, though not the chief, it is in point of order, the first evidence of faith to remember to which side, so ever we turn, that all which meets the eye is the work of God, and at the same time to meditate with pious care on the end which God had in view in creating it. (John Calvin, Institutes of the Christian Religion, I. 14, 20)