a) Did God create the "natural" fermentation process?
b) Did God create humans to be impacted, possibly to drunkenness, by a process that renders squishing of grapes gradually toxic to the human body? In other words, were Adam and Eve, prior to the fall, capable of becoming intoxicated if there was actually a process that God's created fruit of grapes underwent resulting in a fluidic substance that contained a toxin?
Neither of those can be proven no more than one can prove God created a process that would result in squished grapes to develop into a toxin or that he created humans to be able to be impacted by such a toxin to the point of drunkenness. That's all I'm saying.
a. No, but he did charge humans with the cultural mandate to harness the resources of this world in order to reflect God's glory (Gen. 1: 26-28; 2:15)
b. Let me ask a question to answer this question: Did God create humans to be slaughtered by the millions with weapons of bronze and iron? Yet it was part of the development of culture. Bronze and iron were developed by Tubal-Cain from the ungodly, wicked line of Cain (Gen. 4:20-22) yet we have used bronze and iron for tools, sculptures, and many other things that are good. These resources, whether bronze, iron, musical instruments, and even fermented wine are part of God's common grace. But even a hammer (which was made for good) from these tools can be used for bad. Years ago, in our urban ministry, I had a parent of one of our 2nd grade students, that used a hammer to crush another lady's skull, which of course killed her. We don't ban the hammer or the material that the hammer came from because someone used it for evil. My point is, as God's image-bearer, God has given us the responsibility to use these resources for good. It is very possible to use fermented wine for good.
Let me give you an example from my own life. Our inner-city ministry is fraught with stress. I deal with violence on weekly basis (for instance, we had to shut down our basketball program this week because of a fight where a young man threatened to shoot and kill the person he was fighting) When I come home from work, in a situation like this it will take me a couple hours to unwind. Sometimes when I need to really relax, my godly wife will insist that I have a glass of wine. Why? Not because it gives me a buzz because it doesn't. Not because I am trying to drink away my problems.....
No, its because it is a natural way for me to relax and be calm and it helps take away the harsh edge that I would bring home, which used to negatively impact my family. I used to resist this because of all the fundy/prohibition baggage that many of us have talked about. To be honest with you, the only ones that have a problem with me drinking a glass of wine once in a while are the judgmental conservative Christians that don't even have a drinking problem. I rarely bring this up because it just leads to stupid fights and misunderstandings among some of my brothers and sisters in Christ. Its not the alcoholics that I cross paths with.......Now if I was a drunk, then those who struggle with alcohol would also have a major problem with me and would consider me quite the hypocrite and they would be right.
By the way, out of the 20 or so years of doing inner-city ministry where I deal with people who are alcoholics on a weekly basis, I have rarely come across people that accidentally got drunk, which led to their demise. No. There was something much more deep which led them to intentionally use alcohol because they were intentionally trying to get buzzed or drunk in order for them to deal with their internal problems of a failed marriage, abusive father, losing their job, and etc.....